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Dubious Effects of Creatine on Markers of CNS Adaptation and Heart Health in "Bodybuilders" - Reason to Be Afraid?

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Bodybuilding and creatine ain't mentioned in one breath without a reason - Crea simply works! Dozens of studies have shown that... not one, however, tested the effects on the CNS. Based on the extreme excitement I observed in response my recent Facebook News  item on creatine's ability to reduce the sleep requirements in a rodent trial [ (re-)read it ], I assume that you'd like to learn about more or less every study on everyone's favorite ergogenic - correct? Not every study? Oh, yes, obviously, study #103 showing that creatine yields strength and size increases on your average hypertrophy workout would indeed no longer be news-worthy. Much in contrast, however, to a study that claims that creatine may blunt the beneficial effects of resistance training on heart health ? Ok, I see that's getting you excited. So let's take a closer look at how the authors come up with claim... You can learn more about creatine at the SuppVersity Creatine Doubles ...
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Allegedly 'Harmless' Thyroid-Based Fat Burner 3,5-T2 Works Like a Charm, While Commonly Sold 3,3-T2 Could Mess W/ Your Blood Glucose Levels, Liver & Body Fat + Muscle

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These are the kind of abs, you will see on products with T2 and/or T2 and other alleged fat-burners. Don't be fooled by the ads - even if it's the actually active form of diiodothyronine (T2), namely 3,5-T2, you're buying, the pills alone won't get you to the sub-10% body fat range you  may be dreaming of. I've written about the thyroid hormone metabolite  diiodothyronine aka T2 before. Accordingly, you will probably know that it has long been thought of as an inactive byproduct of the thyroid hormone metabolism ( read previous T2-articles ). You will also be aware of the fact that research shows that (a) this is not the case and that (b) only one of its two forms, namely 3,5-diiodothyronine (3,5-T2) shares the fat burning, metabolic effects of its big brother triiodothyronine aka T3. Just like me, you probably don't know, however, why supplement companies are still stupid enough to use both 3,5- and 3,3-diiodothyronine in their allegedly fat burning suppl...
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BroScience Research: "What do Bros Say About AAS Use and the Prevention of Shut Down & Infertility?"

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Are today's "muscle men" not going to be able to procreate? If you are frequenting any of the popular fitness and bodybuilding bulletin boards, you will know that "broscience" is a mixture of anecdotal evidence and hilarious claims that is spiked with cherry picked scientific references. Against that background it may sound funny that researchers from the New Castle Fertility Center  devoted a complete study to the analysis of drugs and protocols highlighted by the online community of users for prevention and/or mitigation of adverse effects of steroid use. If you think about it, however, it's only logical that doctors will be better able to help their patients if they understand what brought them in a situation in which they have to see a doctor at a fertility clinic. Resistance training is the only powerful  muscle builders  with positive health effects! Tri- or Multi-Set Training for Body Recomp.? Alternating Squat & Blood Pressure - Pro...
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Sucralose, Carcinogen or Sweet Relief? Part III: DNA Breaks + Drug & Hormone Interactions | Sucralose, White Death?

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Fearmongering fake, or true biohazard. This is the life-or-death- question this last installment of the sucralose trilogy will have to answer. It's time for the third and last installment of the SuppVersity sucralose review trilogy. Looking back at the list of issues in the first installment of this series, it appears as if the one thing that was still left to discuss are the mutagenic, pro-carcinogenic and tissue damaging effects of sucralose and its potentially endocrine disrupting metabolic / thermic byproducts. It goes without saying that the previously discussed and largely rebutted effects on blood glucose management, body weight gain and even the balance of your gut microbiome would be hardly significant, if today's analysis confirms that the use of Splenda© & Co was linked to direct mutagenic, carcinogenic or general toxic effects. Put your hazard suits on, folks! It's obvious that I got carried away by my imagination, when I wrote this subheading, b...
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Caffeine - 3mg, 6mg or 9mg/kg? What's the Optimal Dosage for Lifting & HIT Cycling and What About the Side Effects?

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Wouldn't a single 200mg caffeine be enough to elicit the desired ergogenic effects without side effect like increased urination, headaches and muscle aches on the day after? Caffeine is not only the world's #1 it is probably also the most (ab-)used ergogenic on the planet and whatever you may think about the longterm consequences of its use, there is not debating that it is part of those few "supplements" that actually work "no hype, no *bs*" ;-) That being said, you may have noticed with yourself that its effect are dose dependent, but not linearly and that some things, such as an increase in mental focus at work require much lower doses of C8H10N4O2 aka 1,3,7-trimethyl-1H-purine-2,6(3H,7H)-dione or 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione than the elucidation of a major buzz before an intense strength workout. So what's the perfect dose, then? Without wanting to hurt your feelings, you may imagine that you are not the only one who has ...
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Better Sip Your Beta Alanine: Decreased Urinary Excretion from Time Released Beta-Alanine Formula.

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Image 1: Tabbing or cabbing, or just washing it down with some water - what is the best way to take your beta alanine? If you have been following the supplement scene for quite some time now, you will probably remember headlines such as " Beta Alanine, the next creatine! "... well, the hype which was deliberately fueled by the supp-companies, who realized that the price umbrella on creatine was shriveling, has abated and yet, beta alanine and, of course, creatine are both still there . Compared to the number of studies on creatine monohodrate, which were and still are published on almost a monthly basis, the science on beta alanine and most importantly its mechanism of action is however pretty skinny. I am thus happy to share with you a few interesting findings from two recently published studies - one today, the other tomorrow ;-) The more it tingles the less it works... !? Despite the fact that I personally like the awkward feeling you get when you take tons of be...
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