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Creatine Non-Responder? Age+Meat Intake - Determinants of Creatine's Effect on PCr (±200%) + Probably Performance

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Vegetarian strength athletes belong to the group of people who will probably benefit most from creatine supplementation. Their young, meat-eating peers, on the other hand, may well turn out to be non-responders, because they see highly individual, but overall only non-significant increases in phosphocreatine. It has been a while since I published the last creatine article ("Dubious Effects of Creatine on Markers of CNS Adaptation and Heart Health in "Bodybuilders" - Reason to Be Afraid?" | read it ); the last time that I addressed the issue of "creatine non-responders", i.e. reasons why people simply don't seem to benefit from creatine supplementation has been published in 2014, already, when I presented the results of a study suggesting that it's not a high dietary creatine intake from meat that makes the difference ( learn more ). Needless to say, meat still made it on the list of possible determinants of the individual performance increase...
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Carnitine Deficiency of Vegetarians Can Be Compensated W/ 2g of L-Carnitine Tartrate Per Day - Unfortunately, Without Measurable Metabolic or Performance Benefits

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Vegetarian athletes do lack carnitine in their diets and muscle, but whether this has significant effects on their performance appears to be questionable based on the results of the study at hand. In a recent study, researchers from the University Hospital Basel investigated whether the previously observed low carnitine levels of vegetarians could be compensated for by longterm oral treatment with 2g of l-carnitine to replenish the body carnitine pool. Furthermore, the scientists wanted to know whether this would have significant effects on (a) fuel metabolism and (b) physical performance of vegetarians and omnivores. Novakova et al. hypothesized that "treatment with carnitine would increase plasma and possibly also skeletal muscle carnitine concentrations in vegetarians and would thereby improve skeletal muscle energy metabolism and physical performance" (Novakova. 2015). Getting enough protein is still a problem for some vegetarians Protein Timing DOES Matter...
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Your Meat Consumption is Probably Not the Reason You're a Creatine Non-Responder: 5% Faster 50m-Sprint Time in 6 Days W/ 20g/day of Creatine for Vegetarians & Omnivores

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It's hard to be a non-responder andno way to change it. In some people the ingestion of creatine appears to be ineffective. Aside from minor diarrhea, when they increase the dosage to the 20g+ range per day in a desperate effort to reap the benefits of one of the, if not the only tried and proven natural ergogenic with significant (real world!) effects, these creatine non-responders don't get any results from either creatine monohydrate or any of the fancier, but mostly inferior "advanced creatines" you can buy at you local, national and international supplement vendor. One of the commonest and eventually most reasonable explanation for "non-responding", I've heard is the hypothesis that non-responders have a high enough creatine intake from meat that would reduce any additional benefit from supplemental creatine to unmeasurable levels. You can learn more about creatine at the SuppVersity Creatine Doubles 'Ur GainZ! Creatine, DHT ...
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