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Pharmacological Starvation: 30% Increased Life Expectancy w/ Still to be Developed FGF21 Analog - The Royal Road To Longevity? Plus: Ground Yourself It's World Nutrition Day!

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Do you really think this kid cares whether there is fructose in his/her banana? Think about that before you delve into the next religious discussion about whether or not food a is legit to eat, "not paleo" or "too high in carbs" *thank you* It's World Food Day and I thought it may be nice to remind everyone about the hilariousness of such "important" first world problems as "eating X bananas a day is bad foryou", the notion of "non paleo" foods and the rest of the vitally important topics the blogosphere is so fond of, these days. Allegedly, neither the bloggers, nor the facebookers or forum posters, who spend so much time and energy debating these and similarly worldshaking issues, will be among the 24,000 human beings who are dieing each and every day from hunger, but maybe one or another of you, of whom I am sure that they don't belong to the group of real notorious nitpickers, will have a similar "grounding experie...
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On Short Notice: Oxytocin to Boost Testosterone & Block Cortisol? Exercise for Life-Extension? Which Tea for Metal-Chelation? Which Fat to Reduce Calorie Intake by ~30%?

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Image 1: This is still my preferred way to boost oxytocin - regardless of possible ergolytic effects ;-) Due to the sudden heat-wave over here in good old Germany I thought, I'd use these early morning hours to get another installment of " On Short Notice " on it's way before my brain dries out (or I drown in the public swimming pool ;-). I hope you enjoy the four items on the recent interest in intranasal the hormone modulating effects of oxytocin , it's effect on cortisol and progesterone, estradiol and (I know you were waiting for that ;-) testosterone, my early morning / late evening (depending on whether you see this from my or Wyatt's perspective) 'intellectual' exchange on the potential longevity effects of exercise and why it probably is not life-extending in the literal sense, the different antioxidant potency of green, black and white tea and their ability to chelate metals (=help to remove all not just "bad" metals from the ...
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Does Your Diet Fail, Because You Sleep Too Little? 40 Min Extra Sleep Will Shed 1 Exta Pound of Fat in 6 Months

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Image 1: Blindfolds are cheaper than light-tight curtains or shutters and they are more versatile ;-) I have repeatedly emphasized the importance of quality sleep, here at the SuppVersity . Based on my own experience sleeping should be your your #1 priority if you want to look good, feel good and perform at your personal best on the cognitive and physiological level into your old age . Unfortunately, the number of controlled long(er)-term studies on the issue is quite small and the epidemiological data either unreliable, inconclusive or both (in most of the cases, the latter is the case; for a review see Nielsen. 2011). I was therefore happy to see that the results of one of the comparatively tightly controlled study from the Healthy Active Living and Obesity Research Group at the Children’s Hospital of Eastern Ontario Research Institute in Canada confirm my personal experience - even if the effect-size was not as pronounced as I would have expected. But let's take one thi...
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What's Worse: YoYo-Dieting or Constant Gluttony? What Happens During Weight Cycling? And Why Does Every Diet Make You Fatter? Lots of Questions, a Couple of Answers

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Image 1: To eat or to diet, what's worse? Despite the fact that the magazines are still full of "X pounds in Y weeks" diets , more and more people begin to realize that "diet hopping" and even "dieting" in the conventional sense, i.e. following a special, usually very strict and non-sustainable nutritional regimen for a very short amount of time, are futile. But can calling a halt before you blow up like a balloon from time to time actually be worse than letting yourself go all-day, everyday? According to the results of an experiment that has been conducted at the Institute of Biology of the State University of Rio de Janeiro , the results of which have just been published in the open access journal PLoSOne , the answer to this question must be: YES, it can! And that may be true, even when you are not starving yourself! Even "healthy" weight cycling turns out to be profoundly unhealthy! Now, the unfortunate news first: We are, as ...
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Adelfo Cerame - Road to The Wheelchair Nationals '12: Back From Thanksgiving and in Better Shape Than Ever!

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Image 1: Some people just know how to improve their physique even when pigging out on thanksgiving. Or can you see any collateral damage the turkey, the pie and the pie and the turkey from last week have done? Assuming that all of you have eventually overcome the physical and psychological consequences of your thanksgiving festivities, you should be about as ready as can be to kickstart the last three serious training weeks of the year. It alway amazes me how long some days (especially those without lectures and tons of paper work in the office) appear to be, when weeks and months fly by like nothing. I remember back in the day, when I first contacted Adelfo on behalf of the Suppversity Student Spotlight and we came up with the idea for this series, I was thinking to myself: "Damn, 2012? That is a going to be a hell long series of blogposts! Let's hope people will like it..." And now? Well, the title of the email I just received from Adelfo is " 2 months down! A...
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Mitohormesis - Suffocated Mitochondria Live Longer: Scientists Probe Longevity-Effect of Low-Level Stressors.

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Image 1: Walter Breuning died in April 2011at the biblical age of 114! And you bet that a man who has seen two world wars has had his share of mitohormetic stress in his life. As a diligent reader of the SuppVersity you will be familiar with the work of S. Schmeisser and M. Ristow from the Department of Human Nutrition at the University of Jena , here in good old Germany (where not everyone eats Sauerkraut und Weisswurst, even now that the Oktoberfest is in full swing). In previous publications, the scientists have (at least in my mind conclusively) argued against the publicly accepted free-radical hypothesis of aging, which implies that the presence of free radicals is one of the fundamental mechanisms of aging. Now, a few month after the publication of their last review back in May 2011, they are presenting the latest results from their own lab in a paper that is going to be published in the October issue of Hormone and Metabolic Research ( Schmeisser. 2011 ) . Want to liv...
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Optimal Weight Loss for Athletes: Lose No More Than 0.7% of Your Body Mass Per Week if You Want to Retain or Even Build Lean Mass While Dieting

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Image 1: Slow dieting paves the way to an aesthetic and strong body A question intricately related to my dissertations in episode #698 of Carl Lenore's Super Human Radio , was and still is the question of the optimal rate, i.e. weight/time, of weight loss to a) maintain a healthy metabolism and b) keep as much muscle mass as possible . While this issue certainly is relevant for the average person, it is of essential importance to an athlete competing in a sport with weight classes. Even if at "weighing day" he or she has the desired body weight, "making" this weight would have been worthless, if he or she had lost too much previous muscle to maintain adequate performance... It is thus surprising that the amount of studies that look into the effects of fast vs. slow weight loss on body composition in an athletic population is rather small, which renders the results of a recent Norwegian study ( Garthe. 2011 ) interesting, all the more. Garthe et al. put a ...
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