NAC Improves Markers of Oxidative Stress Induced by High Intensity Exercise
The word "anti-oxidant" has lost some of its glory within the past couple of years. In absence of overt deficiency, the real-world effects of super high doses of vitamins and other nutrients which have been found to exhibit anti-oxidant activities is negligible if not opposing to the originally intended effect. One of those anti-oxidants which may even produce adverse side effects at very high doses is N-acetyl-cysteine (NAC) . For athletes who expose their bodies to a high amount of oxidative damage, NAC may yet well be a candidate for the list of basic supplements you may want to consider to take. A recent study ( Trevin. 2010 ) involving nine well-trained male cyclists (mean ± SD; 27 ± 6 years of age, VO2peak 69.4 ± 5.8 ml.kg−1.min−1) found that a NAC -loading protocoll consisting of 2 days on 100mg/kg NAC, followed by one day with two servings of 100mg/kg and another dose of 100mg/kg 1h before a 10 minute self-paced time trial, produced the following results: Respirato...