Posts

Showing posts with the label bioavailability

Popular topics

Show more

Guanidinoacetic Acid (GAA) 'Superior' to Creatine in Terms of Bioenergetic & Health Effects on Brain, Muscle & More?

Written by | published on
Image
Not so fast! Just because it may have shuttled more creatine into the muscle GAA does not have to be able to build more strength or size. It has been a while since the last creatine article was published. Luckily, the publication of the latest paper from Sergej M. Ostojic lab at the  University of Novi Sad (Ostojic. 2016b) will change that... as soon as I've analyzed the study and written about it below that is ;-) First things first, we are dealing with a randomized, double-blind, cross-over trial that was financed by a government grant - not non-existing (as of now) supplement companies who are pimping guanidinoacetic acid (GAA) as a "superior new form of creatine". You can learn more about creatine at the SuppVersity Creatine Doubles 'Ur GainZ! Creatine Loading = Unnecessary Creatine Pre or After Workouts? 1st Benefits of Creatine-HCL The Real Bioavai-lability of Crea Build 'Ur Own Buffered Creatine Now, technically speaking, thi...
Read full article »

Creatine Uptake, Bioavailability, and Efficacy - We've Gotten it all Wrong and Low Serum Creatine Levels are Better!?

Written by | published on
Image
If you put some faith into the marketing campaigns of supp producers, there's a creatine for everyone: one to get lean, one to get strong and one to get big and buffed... bullocks! It has been a while since I've discussed the bioavailability of different forms of creatine . On various supplement sites, the notion that there was one form of creatine that was significantly more bioavailable and would thus allow you to 'load' muscle phosphocreatine (PCr) faster and more efficiently is obviously still a matter of constant debate... a debate of which the latest study by Ralf Jäger et al. (2016) indicates that it may argue based on a fundamentally flawed premise, i.e. that higher serum levels of creatine after the ingestion of a given product would signify an increased efficacy in terms of performance / strength / size gains. How come? Well, the previously mentioned, as of yet unpublished data from a study by Ralf Jäger, Martin Purpura, and Roger C Harris did not just ...
Read full article »

Want to Home-Brew Your Own 15x More Bioavailable Super-Curcumin? Buy Buttermilk and a Yogurt Starter Culture

Written by | published on
Image
No one says you cannot add other ingredients to the yogurt to make it more tasty if you add the curcumin before fermenting the buttermilk. If you're a regular at the SuppVersity  you will know that curcuminoids, the polyphenols found in turmeric roots (Curcuma longa), have health effects that are similar, in some cases even superior to several anti-inflammatory, anti-diabetic and lipid-lowering drugs. Yes, their consumption has even been linked to significant reductions in cancer risk. Unfortunately, there's a problem with these powerful polyphenols: they are hydrophopbic (Tønnesen. 2002) and prone to degradation in an aqueous environment at neutral and alkaline pH (Tønnesen. 1985; Wang. 1997) - two properties of which Gupta and others (2013) believe that they are responsible their poor oral bioavailability. Unlike other supps and practices curcumin has not been shown to interfere with hormesis Is Vitamin E Good for the Sedentary Slob, Only? Even Ice-Baths Impair ...
Read full article »

60%+ Reduced Absorption of EGCG if You Consume GTE W/ Food - Better Take Your Green Tea Caps On Empty

Written by | published on
Image
Green tea smoothies - If you don't want to waste more than 60% of green tea's precious EGCG content, you better don't blend it with too much other stuff While the previously discussed effect of milk on the bioavailability of the polyphenols from green tea (the beverage) is probably negligible, a recent study from the University of Cranberra  suggests that the inhibitory effect of food on the absorption of the major catechins in green tea may be significant enough to say that it's important to take them away from food. To assess the effects of different food matrices on the bioavailability of capsulated green tea supplements, Naumovski et al. came up with a systemic absorption test healthy fasted humans. You can learn more about tea at the SuppVersity Use Roiboos for Stress & Virus Control Tired? Theacrine Will Get You Goin' in Minutes Milk, Tea & Honey Don't Mix?! Theacrine or Caffeine for Brain Power? Aluminum, Lead & Arsen...
Read full article »

Supplement Sensation? Oral Glutathione Supplements Dose-Dependently Double GSH in Randomized Controlled Human Studies. Health Implications Still to Be Determined

Written by | published on
Image
Blueberries and other foods w/ tons of polyphenols are GSH boosters (Moskaug. 2005) and make supplements obsolete.  If you have been interested in dietary supplements for some time, I am pretty sure that you will have heard about oral glutathione ob(GSH) supplements in one of the "snake oil warnings" on various websites. The "master antioxidant" as it is called is after all believed by many to be not bioavailable - at least not orally. Studies in animal models, however, have already shown that oral GSH, administered either in the diet or by gavage, has the ability to increase plasma and tissue GSH levels ( Loven. 1986; Aw. 1991; Favilli. 1997; Kariya. 2007). It would thus be more appropriate to say that the efficacy of oral glutathione in humans has not yet been tested in peer-reviewed studies. You can learn more about potential negative sides of too many / the wrong antioxidants : NAC = GSH ￪, Anabolism ￬ Too Much "Vit C" For Gains? Protei...
Read full article »
Disclaimer:The information provided on this website is for informational purposes only. It is by no means intended as professional medical advice. Do not use any of the agents or freely available dietary supplements mentioned on this website without further consultation with your medical practitioner.