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Artificial Sweetener Saccharin Increases Weight Gain in Rodent Study Without Increasing Food Intake | Plus: Meta-Analysis of Human Studies Says: "No Reason to Worry!"

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Should you freak out about a small increase in body weight in a small-scale rodent study that is attributed to the consumption of saccharin in yogurt? While epidemiological studies show that the consumption of products containing non-nutritive sweeteners (NNS) is associated with increased adiposity (Colditz. 1990; Fowler. 2008), type 2 diabetes mellitus (T2DM), metabolic syndrome and cardiovascular disease (Dhingra. 2007; Lutsey, Steffen. 2008). A mechanistic link between aspartame, sucralose, stevia & co and weight gain as well as its ill metabolic and cardiovascular consequences in humans is non-existent  ( learn more ). Rather than weight increases controlled human studies show that the consumption of artificially sweetened foods promote, not hinder the loss of body fat  (Sørensen. 2014). You can learn more about sweeteners at the SuppVersity Aspartame & Your Microbiome - Not a Problem? Will Artificial Sweeteners Spike Insulin? Sweeteners & ...
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GABA Supplementation Improves Glucose Management - Even in Healthy Subjects | Significant Reduction in Glycated Albumin Levels After Only 7 Days on 3x2g GABA per Day

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No acute changes in blood glucose, but extreme changes in insulin levels. How can this trigger a reduction in glycated albumin - How's that possible?  You've read about gamma aminobutyric acid (GABA) at the SuppVersity  before. While most people think of it mainly as a calming agent, though, SuppVersity  readers know that it has the remarkable ability to heal the insulin producing β-cell in rodents by stimulating their replication, protecting them against apoptosis, and attenuating insulitis (Soltani. 2011; Tian. 2013; Prud'homme. 2014; Purwana. 2014). And while these favorable effects were first observed in mice, researchers are quite sure that they are valid in humans, too- that's also because said effects have been confirmed only recently by Tian et al. (2014) and Purwana et al. (2014) in vitro as well as in xenotransplanted human islets. Learn more about the effects of GABA & co at the SuppVersity GABA Diabesity Treatment Phenibut Addic- tive ...
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World Diabetes Day: Is Bariatric Surgery the Only Tool to Send T2DM into Remission? Adherence to 6 Months of Daily Exercise and Eating 500kcal/day Less Works, Too!

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Diabetes is a disease that is currently often only managed, not treated and that despite the fact that scientists know ways to send T2DM it into remission. With the 14th of November being the World Diabetes Day , I thought it may be worth taking a look at the available evidence on treating , not just managing diabetes. If you do just that, there is one treatment that sticks out: Bariatric surgery. There is currently little doubt that weight loss surgery is the most promising tool doctors have to actually "treat" type II diabetes. As Esposito et al. point out in their recent review of the literature,  "more information is [however] needed about the long-term durability of comorbidity control and complications after bariatric procedures" (Esposito. 2015). Educate yourself @ www.suppversity.com do battle or avoid T2DM Pasta "Al Dente" = Anti-Diabetic Vinegar & Gums for Weight Loss Nutrient Deficien- cies in the US Yohimbine Burns Stub...
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Health & Weight Loss Start in the Gut: Probiotics Trigger Fat Loss Without Dieting | Casein Improves Lipid Metabolism

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Gut health is "all the rage", lately. So even if it's true that this may be one of the most culpably neglected areas of research in the past century, we should still be careful not to hype the effect of the gut on your physique and health too much. Well, probiotics and the human microbiome (the one in the gut and  elsewhere) are all the rage, these days. Against that background, it's not really surprising that a probiotic supplement and thus a human microbiome modulator made it into the SuppVersity  news ( again ). What may be surprising, though, is the fact that casein didn't just do the same, but that its appearance here in the news is not  due to its muscle building prowess. Rather than that, casein made the cut, because a recent study by Francois Mariotti, et al. shows that - even in comparison to whey protein - casein attenuates the potentially unhealthy postprandial triglyceride response to a mixed high-fat meal in healthy, overweight men. You can lea...
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Nine Short Workouts (AM+PM) p. Week Yield Extra Strength, Size and Performance Gains Compared to Volume Matched 3-Day Split, All Differences are Non-Significant, Though

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15 min in the AM, 15 in the PM = Win? For many of you that may sound laughable, but according to a recent study from the University   of Copenhagen  it is at least as effective as three "mammoth" workouts-sessions per week. What kind of trainee are you? Do you hit the gym thrice a week, spend two hours there and crawl out of the gymdoors totally exhausted? Yeah... Well that means you're not the fitness model guy, who trains twice a day for 15-20 minutes only and swears that this is the only way to do it? After all these questions you're probably asking yourself if the answers you gave in your mind were good or bad for ya? Right? Well, eventually, both forms of training can be equally effective. If we take a closer look at the non-significant study outcomes in a recent paper by scientists from the University of Copenhagen (Kilen. 2015), though body composition and strength may in fact benefit more if you train more frequently - even  if the total workout volume...
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