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The Vampire Approach to Longevity - Young Blood Revives Muscle, Brain & More | Plus: 6+ Less 'Horrific' Alternatives

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Download the podcast this article relates to at superhumanradio.net You will probably remember from the SuppVersity  Facebook news (@SuppVersity |  March 15, 2018 ) that scientists believe that they've found the molecule that's responsible for the rejuvenating effects of "young blood". In their study, which expanded on rodent data indicating that the injection of "young blood", i.e. blood from young mice, into the circulation of old(er) mice has multi-dimensional rejuvenating effects, the researchers grew  human  muscle cells (C2C12 myoblasts) in a petri dish and stimulated them w/ media conditioned with 5% plasma from healthy male participants that were either younger (n = 6, 18–35) or older (n = 6, >57 years). What Kalampouka et al. ( 2018 ) observed was that the muscle cells reacted differently to a stimulus in form of a scratch (intended to simulate muscular injury and recovery) depending on whether the cultured in media conditioned plasma from ...
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More Than a Diet Myth? Dark Chocolate/Cacao Won't Get You Jacked, but it May Help Maintain a Slim Waist Over Time

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Dark  chocolate & body comp? I am not a fan of referring to the hierarchy of evidence ( Haidich 2010 , Figure 1 ) to justify discussing a meta-analysis (in itself a mix of statistical data analysis and, you guessed it, the discussion of individual RCTs and/or observational studies) but I guess in the case of the putative weight-loss benefits of dark chocolate, I can make an exception. How come? Well, if you do a cursory review of the experimental evidence you will realize pretty soon that the term "conflicting" is not strong enough to describe what you see. Accordingly, I am grateful that a group of Iranian researchers conducted a meta-analysis of all relevant RCTs investigating the impact of cocoa/DC on body weight, body mass index (BMI) and waist circumference (WC). You can learn more about chocolate and cacao at the SuppVersity Chocolicious Statin 4 Women Real Cacao Delicious + More The Chocolate Diet for Women Cacao for the Gut Micro...
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2.5 mg Nicotine = Ergogenic - 18-21% Increase in Power in Crossover Study | Plus: Are Health or Addiction an Issue?

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While cigarettes are neither effective performance enhancers nor safe, nicotine, one of their key ingredients, may be the effective ergogenic aid with a reasonable sides/effects ratio you have been looking for... well, that's at least what the recently published 1st RCT with reliability test and crossover protocol seems to suggest. Yes, nicotine is the main (psycho-)active ingredient in cigarette smoke. It is, however, - and we tend to forget that in the debate about (ab-)using nicotine as a "supplement" - only one out of many "ingredients" of cigarette smoke; ingredients that ruin the health of our lungs and promote the risk of lung and other cancers. It would be haphazard, though, to exonerate nicotine completely, as there is "a direct contribution of nicotine to cancer onset and growth" ( Grando 2017 ). The research on the interaction of individual genetic susceptibility and nicotines ability to activate "nicotinic acetylcholine receptors...
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Every-Other-Day 'Fasting' in Trained Athletes: Effects Range from Fat Loss to Significant Performance Enhancement

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ADF -esque diet strategy w/ dieting vs. fasting works for "athletes", too. Intermittent fasting in its various incarnation (aka "lean gains" = 6/18, "every-other-day", "2-3 weekly fasting days, etc.) are getting more and more popular and science shows: # Fasting is probably not just a fad. In fact, the number of RCTs to confirm beneficial effects on body composition, inflammation, heart and brain health, etc. increases by the day. The latest addition to the accumulating research has just been published in the Journal of the ISSN ; although, technically speaking it is rather an alternate days dieting regimen with a comparatively mild deficit of 33%. In their paper, Victoria Pons et al. ( 2018 ) aimed to "evaluate the effects of every-other-day feeding CR interventions on the body composition and physical performance parameters (during maximal exercise tests) of well-trained athletes" (Pons 2018). Learn more about fasting at the Sup...
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